J Alfredo Martínez Selected Research

Thioctic Acid (Lipoic Acid)

5/2018	Effects of EPA and lipoic acid supplementation on circulating FGF21 and the fatty acid profile in overweight/obese women following a hypocaloric diet.
5/2018	Untargeted metabolomic on urine samples after α-lipoic acid and/or eicosapentaenoic acid supplementation in healthy overweight/obese women.
1/2017	Effects of dietary supplementation with EPA and/or α-lipoic acid on adipose tissue transcriptomic profile of healthy overweight/obese women following a hypocaloric diet.
3/2016	Effects of alpha-lipoic acid on chemerin secretion in 3T3-L1 and human adipocytes.
4/2015	Supplementation with α-Lipoic Acid Alone or in Combination with Eicosapentaenoic Acid Modulates the Inflammatory Status of Healthy Overweight or Obese Women Consuming an Energy-Restricted Diet.
3/2015	α-Lipoic acid treatment increases mitochondrial biogenesis and promotes beige adipose features in subcutaneous adipocytes from overweight/obese subjects.
2/2015	Effects of α-lipoic acid and eicosapentaenoic acid in overweight and obese women during weight loss.
10/2014	α-lipoic acid reduces fatty acid esterification and lipogenesis in adipocytes from overweight/obese subjects.
12/2012	Lipoic acid administration prevents nonalcoholic steatosis linked to long-term high-fat feeding by modulating mitochondrial function.
9/2011	Effects of lipoic acid on apelin in 3T3-L1 adipocytes and in high-fat fed rats.

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J Alfredo Martínez Research Topics

Disease

82	Obesity 09/2022 - 08/2002
44	Overweight 09/2022 - 01/2002
43	Weight Loss (Weight Reduction) 01/2022 - 01/2003
40	Metabolic Syndrome (Dysmetabolic Syndrome X) 09/2022 - 07/2006
39	Insulin Resistance 07/2021 - 03/2002
35	Body Weight (Weight, Body) 10/2022 - 01/2002
23	Inflammation (Inflammations) 01/2022 - 10/2008
19	Cardiovascular Diseases (Cardiovascular Disease) 03/2022 - 12/2008
17	Non-alcoholic Fatty Liver Disease 06/2022 - 12/2011
11	Type 2 Diabetes Mellitus (MODY) 01/2021 - 01/2009
10	Weight Gain 01/2021 - 02/2006
9	Fatty Liver 06/2021 - 09/2009
6	Hypertension (High Blood Pressure) 09/2022 - 11/2005
5	Necrosis 08/2019 - 02/2007
5	Hyperglycemia 01/2019 - 10/2005
4	Neoplasms (Cancer) 01/2021 - 05/2010
4	Abdominal Obesity 01/2020 - 05/2006
3	COVID-19 01/2022 - 01/2020
3	Metabolic Diseases (Metabolic Disease) 02/2021 - 04/2019
3	Hypoxia (Hypoxemia) 01/2021 - 06/2012
3	Glucose Intolerance 05/2020 - 06/2010
3	Prediabetic State (Prediabetes) 01/2019 - 10/2009
3	Chronic Disease (Chronic Diseases) 01/2017 - 03/2010
2	Cognitive Dysfunction 01/2022 - 08/2021
2	Peripheral Arterial Disease 10/2021 - 12/2020
2	Infections 01/2020 - 04/2002
2	Hypertriglyceridemia 01/2019 - 01/2018
2	Dyslipidemias (Dyslipidemia) 01/2019 - 09/2013

Drug/Important Bio-Agent (IBA)

33	Glucose (Dextrose)FDA LinkGeneric 10/2022 - 03/2002
28	Biomarkers (Surrogate Marker)IBA 01/2022 - 01/2009
23	LipidsIBA 10/2021 - 01/2006
22	AntioxidantsIBA 04/2021 - 06/2006
20	Insulin (Novolin)FDA Link 07/2021 - 03/2002
18	LeptinIBA 08/2019 - 03/2002
17	Triglycerides (Triacylglycerol)IBA 10/2022 - 01/2009
15	Proteins (Proteins, Gene)FDA Link 09/2022 - 01/2002
12	CarbohydratesIBA 01/2021 - 01/2003
12	Thioctic Acid (Lipoic Acid)IBA 05/2018 - 06/2011
11	HDL CholesterolIBA 12/2020 - 06/2011
11	Fatty Acids (Saturated Fatty Acids)IBA 10/2019 - 07/2006
11	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 04/2019 - 02/2007
9	CholesterolIBA 01/2020 - 12/2005
9	AdipokinesIBA 01/2019 - 10/2008
8	Dietary Fats (Dietary Fat)IBA 05/2021 - 09/2010
8	MicroRNAs (MicroRNA)IBA 01/2021 - 01/2013
8	Interleukin-6 (Interleukin 6)IBA 08/2020 - 12/2007
8	AdiponectinIBA 08/2019 - 02/2007
8	Eicosapentaenoic AcidIBA 04/2019 - 02/2007
8	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 08/2017 - 04/2004
6	LDL CholesterolIBA 08/2020 - 12/2008
6	Hormones (Hormone)IBA 07/2019 - 07/2006
6	GhrelinIBA 02/2015 - 04/2004
5	Folic Acid (Vitamin M)FDA LinkGeneric 03/2021 - 02/2016
5	Olive OilIBA 12/2020 - 01/2002
5	Messenger RNA (mRNA)IBA 08/2019 - 04/2007
5	C-Reactive ProteinIBA 04/2015 - 01/2009
4	CreatinineIBA 07/2021 - 06/2019
4	Amino Acids FDA Link 06/2021 - 10/2007
4	PolyphenolsIBA 04/2021 - 05/2011
4	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 04/2019 - 09/2015
4	CytokinesIBA 09/2015 - 06/2011
3	Indicators and Reagents (Reagents)IBA 10/2021 - 10/2009
3	AlbuminsIBA 07/2021 - 02/2021
3	FructoseIBA 05/2021 - 12/2005
3	ResveratrolIBA 05/2021 - 06/2011
3	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 06/2013
3	Apolipoproteins E (ApoE)IBA 01/2020 - 11/2008
3	Choline (Choline Chloride)IBA 01/2020 - 02/2016
3	Interleukin-18 (Interleukin 18)IBA 08/2019 - 09/2015
3	Plasminogen Activator Inhibitor 1IBA 09/2015 - 06/2011
3	ApelinIBA 04/2015 - 04/2009
3	EnzymesIBA 10/2014 - 06/2012
3	SeleniumIBA 10/2011 - 01/2009
3	oxidized low density lipoproteinIBA 08/2011 - 04/2007
3	Nicotinamide PhosphoribosyltransferaseIBA 06/2011 - 04/2009
3	EstersIBA 09/2009 - 02/2007
2	Coffee FDA Link 08/2021 - 01/2021
2	Caffeine (No Doz)FDA LinkGeneric 08/2021 - 01/2021
2	Ferritins (Ferritin)IBA 07/2021 - 11/2020
2	Docosahexaenoic AcidsIBA 02/2021 - 06/2015
2	Alanine Transaminase (SGPT)IBA 11/2020 - 08/2020
2	Malondialdehyde (Propanedial)IBA 08/2020 - 04/2007
2	Omega-6 Fatty Acids (Omega 6 Fatty Acids)IBA 05/2020 - 08/2018
2	AcidsIBA 05/2020 - 09/2009
2	Betaine (C.B.B.)FDA Link 01/2020 - 02/2016
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2020 - 08/2019
2	Methionine (L-Methionine)FDA Link 01/2020 - 01/2018
2	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2020 - 01/2019
2	Interleukin-1beta (Interleukin 1 beta)IBA 08/2019 - 01/2018
2	Vitamin B 12 (Cyanocobalamin)FDA LinkGeneric 01/2018 - 02/2016
2	Serotonin (5 Hydroxytryptamine)IBA 01/2018 - 06/2012

Therapy/Procedure

22	Mediterranean Diet 09/2022 - 09/2010
7	Therapeutics 01/2021 - 08/2002
6	Caloric Restriction 04/2011 - 09/2004
4	Precision Medicine 01/2022 - 01/2020
4	Fat-Restricted Diet (Diet, Fat Restricted) 01/2020 - 06/2006
2	Length of Stay 01/2022 - 10/2021
2	Glycemic Control 01/2020 - 01/2019
2	High-Protein Diet 01/2020 - 06/2018
2	Obesity Management 07/2019 - 01/2013